BMS8012

This course will explore relevant aspects of Human Genetics, from gene structure to function and dysfunction, to provide you with the knowledge to understand how genetics influences health and disease. With the advent of technologies for genome sequencing and genetic manipulation, genetics has become a central science in biomedical research with the power to explain the origin of human disease, predict health risks, and dream about near future therapies. Massive sequencing capabilities have increased the pace of genetic discoveries, uncovering the molecular mechanisms underpinning human diseases: from rare monogenetic disorders to complex multigenic disorders. The power of genetic technologies also creates new legal and ethical problems, as illustrated by the recent CRISPR baby. The course will discuss in depth the current science of Human Genetics along with the legal and societal implications brought upon by the new knowledge and technologies. The course will follow a student presentation - class discussion format for several relevant topics. Students will also create a Concept Map for a particular disease that will require independent research and teamwork.

pre-req: Undergrad genetics (BIOL 2201 and BIOL 4231 in UMD) or instructor consent

012410

Every Fall